Assay Detail
Binding
CHEMBL807186
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Transcriptional activation of retinoid X receptor RXR alpha; not active
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Synthesis and pharmacological activity of conformationally restricted, acetylenic retinoid analogs
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 5.00 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL275311 | — | — | 1 | 5.00 |
| CHEMBL151870 | — | — | 1 | 5.00 |
| CHEMBL151672 | — | — | 1 | - |
| CHEMBL147335 | — | — | 1 | - |
| CHEMBL150583 | — | — | 1 | - |
| CHEMBL38 | TRETINOIN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL275311 | — | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL151870 | — | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL151672 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL147335 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL150583 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL38 | TRETINOIN | EC50 | > | 10000.0 | nM | - |