Assay Detail
Binding
CHEMBL809131
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Compound was evaluated for its inhibitory activity against recombinant rat SE(squalene epoxidase)
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Inhibition of vertebrate squalene epoxidase by isoprenyl gallates and phenylalkyl gallates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.36 | 7.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL16121 | DODECYL GALLATE | — | 1 | 7.21 |
| CHEMBL297453 | EPIGALOCATECHIN GALLATE | 3.0 | 1 | 6.16 |
| CHEMBL85001 | — | — | 1 | 5.82 |
| CHEMBL82679 | — | — | 1 | 5.35 |
| CHEMBL312495 | — | — | 1 | 5.29 |
| CHEMBL83943 | — | — | 1 | 4.92 |
| CHEMBL420405 | — | — | 1 | 4.90 |
| CHEMBL85907 | Geranyl gallate | — | 1 | 4.90 |
| CHEMBL83999 | — | — | 1 | 4.82 |
| CHEMBL84925 | — | — | 1 | 4.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL16121 | DODECYL GALLATE | IC50 | = | 61.0 | nM | 7.21 |
| CHEMBL297453 | EPIGALOCATECHIN GALLATE | IC50 | = | 690.0 | nM | 6.16 |
| CHEMBL85001 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL82679 | — | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL312495 | — | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL83943 | — | IC50 | = | 11900.0 | nM | 4.92 |
| CHEMBL420405 | — | IC50 | = | 12500.0 | nM | 4.90 |
| CHEMBL85907 | Geranyl gallate | IC50 | = | 12500.0 | nM | 4.90 |
| CHEMBL83999 | — | IC50 | = | 15300.0 | nM | 4.82 |
| CHEMBL84925 | — | IC50 | = | 61300.0 | nM | 4.21 |