Assay Detail
Binding
CHEMBL809133
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for its inhibitory activity against squalene epoxidase from rat liver microsomes
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Liver |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Epoxidation of 6,7- and 10,11-oxidosqualenes by the squalene epoxidase present in rat liver microsomes
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.16 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL86248 | — | — | 1 | 6.96 |
| CHEMBL177752 | — | — | 1 | 4.89 |
| CHEMBL22049 | — | — | 1 | 4.50 |
| CHEMBL316024 | — | — | 1 | 4.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL86248 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL177752 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL22049 | — | IC50 | = | 31800.0 | nM | 4.50 |
| CHEMBL316024 | — | IC50 | = | 50900.0 | nM | 4.29 |