Assay Detail
Binding
CHEMBL809288
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition against TXA2/PGH2 receptor using [3H]-SQ 29,548 as radioligand in human platelet membrane preparation
5
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Thoromboxane A2/endoperoxide receptor antagonists: 1,3-Dioxane and 1,3-dioxolane analogs
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.71 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL278159 | — | — | 1 | 8.15 |
| CHEMBL23273 | — | — | 3 | 6.89 |
| CHEMBL280890 | — | — | 1 | 6.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL278159 | — | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL23273 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL23273 | — | IC50 | = | 310.0 | nM | 6.51 |
| CHEMBL280890 | — | IC50 | = | 330.0 | nM | 6.48 |
| CHEMBL23273 | — | IC50 | = | 3100.0 | nM | 5.51 |