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Assay Detail

CHEMBL809290

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was tested in vitro for antagonistic activity against thromboxane receptor.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Thromboxane A2 receptor (CHEMBL2069)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Development of dual-acting agents for thromboxane receptor antagonism and thromboxane synthase inhibition. 3. Synthesis and biological activities of oxazolecarboxamide-substituted omega-phenyl-omega-(3-pyridyl)alkenoic acid derivatives and related compounds.
Takeuchi K, Kohn TJ, True TA, Mais DE, Wikel JH, Utterback BG, Wyss VL, Jakubowski JA.
J Med Chem (1998) 41 : 5362 -5374
PubMed 9876106 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL299467 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL299467 Kd = 9.9 nM 8.00