Assay Detail
Binding
CHEMBL809292
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In vitro binding affinity was determined for platelet thromboxane receptor in presence of [3H]-SQ 29548
6
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Thoromboxane A2/endoperoxide receptor antagonists: 1,3-Dioxane and 1,3-dioxolane analogs
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 6 | 8.06 | 8.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL278159 | — | — | 1 | 8.89 |
| CHEMBL283100 | BMS-180291 | — | 1 | 8.40 |
| CHEMBL280890 | — | — | 1 | 8.10 |
| CHEMBL23273 | — | — | 3 | 8.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL278159 | — | Kd | = | 1.3 | nM | 8.89 |
| CHEMBL283100 | BMS-180291 | Kd | = | 4.0 | nM | 8.40 |
| CHEMBL280890 | — | Kd | = | 8.0 | nM | 8.10 |
| CHEMBL23273 | — | Kd | = | 8.2 | nM | 8.09 |
| CHEMBL23273 | — | Kd | = | 31.1 | nM | 7.51 |
| CHEMBL23273 | — | Kd | = | 45.0 | nM | 7.35 |