Assay Detail
Functional
CHEMBL809306
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In vitro effective concentration against HIV-1 cytopathic effect in T4 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | T4 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of certain alpha,beta-unsaturated ketones and their corresponding fused pyridines as antiviral and cytotoxic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.67 | 9.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL129 | ZIDOVUDINE | 4.0 | 1 | 9.15 |
| CHEMBL100326 | — | — | 1 | 4.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL129 | ZIDOVUDINE | EC50 | = | 0.7 | nM | 9.15 |
| CHEMBL100326 | — | EC50 | = | 64700.0 | nM | 4.19 |