Assay Detail
Functional
CHEMBL810503
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Tested for inhibition of contractile effects of Tachykinin receptor 1 in guinea pig ileum preparation.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Synthesis of RP-67,580, a new potent nonpeptide substance P antagonist
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 7.20 | 7.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL131171 | — | — | 1 | 7.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL131171 | — | Kd | = | 63.1 | nM | 7.20 |