Assay Detail
Binding
CHEMBL810933
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In vitro activity against thrombin was determined
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Retro-binding tripeptide thrombin active-site inhibitors: discovery, synthesis, and molecular modeling.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.51 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL273196 | EFEGATRAN | 2.0 | 1 | 8.10 |
| CHEMBL308232 | — | — | 1 | 6.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL273196 | EFEGATRAN | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL308232 | — | IC50 | = | 120.0 | nM | 6.92 |