Assay Detail
Binding
CHEMBL811275
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for its binding affinity at Thromboxane A2 receptor by measuring its ability to displace [3H]U-46619 from guinea pig platelets at 0.1 uM
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Non-prostanoid thromboxane A2 receptor antagonists with a dibenzoxepin ring system. 1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.04 | 8.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL324364 | — | — | 1 | 8.19 |
| CHEMBL8273 | SULOTROBAN | 2.0 | 1 | 5.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL324364 | — | Ki | = | 6.5 | nM | 8.19 |
| CHEMBL8273 | SULOTROBAN | Ki | = | 1300.0 | nM | 5.89 |