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Assay Detail

CHEMBL811279

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Concentration producing half-maximal inhibition of specific binding of [3H]senktide to Tachykinin receptor 3 in the guinea pig cerebral cortex
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Tissue Cerebral cortex
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Neuromedin-K receptor (CHEMBL4429)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

2,3-Substituted 2-azanorbornanes as polar -turn mimetics
Horwell DC, Naylor D, Willems HM
Bioorg Med Chem Lett (1997) 7 : 31 -36
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.46 5.46

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL32940 1 5.46

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL32940 IC50 = 3500.0 nM 5.46