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Assay Detail

CHEMBL812060

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity of compound was evaluated towards tachykinin receptor 2 by using radioligand ([125I]-NKA in rat duodenum
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Substance-K receptor (CHEMBL4554)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Imidazo[4,5-b]quinoxaline cyanines as neurokinin antagonists.
Appell KC, Babb BE, Goswami R, Hall PL, Lawrence KB, Logan ME, Przyklek-Elling R, Tomczuk BE, Venepalli BR, Yanni JM.
J Med Chem (1991) 34 : 1751 -1753
PubMed 1851847 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.77 5.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL278294 1 5.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL278294 IC50 = 1700.0 nM 5.77