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Assay Detail

CHEMBL812087

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory concentration on human T-lymphocyte Molt4 (clone 8) cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MOLT-4
Confidence 1 — Organism
Curated By Intermediate

Target

Homo sapiens (CHEMBL372)
Type ORGANISM
Organism Homo sapiens

Publication

Antiviral enantiomeric preference for 5'-noraristeromycin.
Siddiqi SM, Chen X, Schneller SW, Ikeda S, Snoeck R, Andrei G, Balzarini J, De Clercq E.
J Med Chem (1994) 37 : 551 -554
PubMed 8120872 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.87 6.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL129014 NORARISTEROMYCIN 1 6.41
CHEMBL2051948 1 5.33

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL129014 NORARISTEROMYCIN IC50 = 390.0 nM 6.41
CHEMBL2051948 IC50 = 4650.0 nM 5.33