Assay Detail
Functional
CHEMBL812944
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Compound was evaluated for its antiproliferative activity on human T-lymphocyte Molt4/C8 cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MOLT-4 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and antiproliferative activity of 2-O-allyl-1--D-arabinofuranosyl-uracil, -cytosine and -adenine
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.50 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL803 | CYTARABINE | 4.0 | 1 | 7.52 |
| CHEMBL1090 | VIDARABINE | 4.0 | 1 | 4.92 |
| CHEMBL3142859 | — | — | 1 | 4.06 |
| CHEMBL100259 | URIDINE | 3.0 | 1 | - |
| CHEMBL3142860 | — | — | 1 | - |
| CHEMBL3142861 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL803 | CYTARABINE | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL1090 | VIDARABINE | IC50 | = | 11900.0 | nM | 4.92 |
| CHEMBL3142859 | — | IC50 | = | 88000.0 | nM | 4.06 |
| CHEMBL100259 | URIDINE | IC50 | > | 200000.0 | nM | - |
| CHEMBL3142860 | — | IC50 | > | 500000.0 | nM | - |
| CHEMBL3142861 | — | IC50 | = | 588000.0 | nM | - |