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Assay Detail

CHEMBL813013

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in hamster serum
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Cholesteryl ester transfer protein (CHEMBL3572)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery of a simple picomolar inhibitor of cholesteryl ester transfer protein.
Reinhard EJ, Wang JL, Durley RC, Fobian YM, Grapperhaus ML, Hickory BS, Massa MA, Norton MB, Promo MA, Tollefson MB, Vernier WF, Connolly DT, Witherbee BJ, Melton MA, Regina KJ, Smith ME, Sikorski JA.
J Med Chem (2003) 46 : 2152 -2168
PubMed 12747787 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.14 7.14

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL67129 1 7.14

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL67129 IC50 = 73.0 nM 7.14