Assay Detail
ADMET
CHEMBL813065
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Bioavailability after peroral administration at 30 mg/kg against Stromelysin in rat
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
NMR-based modification of matrix metalloproteinase inhibitors with improved bioavailability.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.86 | 7.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL38851 | — | — | 1 | 7.24 |
| CHEMBL152350 | — | — | 1 | 6.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL38851 | — | IC50 | = | 57.0 | nM | 7.24 |
| CHEMBL152350 | — | IC50 | = | 340.0 | nM | 6.47 |