Assay Detail
Binding
CHEMBL813181
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for the inhibitory activity against Steroid 5-alpha-reductase in rat
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Structure activity relationship study of known inhibitors of the enzyme 5 alpha-reductase (5AR).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.62 | 9.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL133338 | — | — | 1 | 9.89 |
| CHEMBL134224 | — | — | 1 | 8.20 |
| CHEMBL3349181 | — | — | 1 | 7.39 |
| CHEMBL132778 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL133338 | — | IC50 | = | 0.13 | nM | 9.89 |
| CHEMBL134224 | — | IC50 | = | 6.3 | nM | 8.20 |
| CHEMBL3349181 | — | IC50 | = | 41.0 | nM | 7.39 |
| CHEMBL132778 | — | IC50 | = | 10000.0 | nM | 5.00 |