Assay Detail
Binding
CHEMBL813564
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Compound was evaluated for its inhibitory activity against human thrombin
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Potent and efficacious thienylamidine-incorporated thrombin inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 8.68 | 9.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL7962 | — | — | 1 | 9.42 |
| CHEMBL296956 | — | — | 1 | 9.31 |
| CHEMBL48133 | — | — | 1 | 9.22 |
| CHEMBL46842 | — | — | 1 | 9.08 |
| CHEMBL298013 | — | — | 1 | 8.52 |
| CHEMBL7656 | — | — | 1 | 8.17 |
| CHEMBL47908 | — | — | 1 | 7.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL7962 | — | Ki | = | 0.38 | nM | 9.42 |
| CHEMBL296956 | — | Ki | = | 0.49 | nM | 9.31 |
| CHEMBL48133 | — | Ki | = | 0.6 | nM | 9.22 |
| CHEMBL46842 | — | Ki | = | 0.84 | nM | 9.08 |
| CHEMBL298013 | — | Ki | = | 3.0 | nM | 8.52 |
| CHEMBL7656 | — | Ki | = | 6.8 | nM | 8.17 |
| CHEMBL47908 | — | Ki | = | 91.0 | nM | 7.04 |