Assay Detail
Binding
CHEMBL813617
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Inhibitory concentration against thrombin.
9
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Secondary structure peptide mimetics: design, synthesis, and evaluation of beta-strand mimetic thrombin inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 8.86 | 10.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL28817 | — | — | 1 | 10.15 |
| CHEMBL28365 | — | — | 1 | 10.14 |
| CHEMBL283022 | — | — | 1 | 9.51 |
| CHEMBL29309 | — | — | 1 | 9.35 |
| CHEMBL282830 | — | — | 1 | 9.19 |
| CHEMBL27852 | — | — | 2 | 9.07 |
| CHEMBL28922 | — | — | 1 | 8.62 |
| CHEMBL285140 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL28817 | — | Ki | = | 0.071 | nM | 10.15 |
| CHEMBL28365 | — | Ki | = | 0.073 | nM | 10.14 |
| CHEMBL283022 | — | Ki | = | 0.31 | nM | 9.51 |
| CHEMBL29309 | — | Ki | = | 0.45 | nM | 9.35 |
| CHEMBL282830 | — | Ki | = | 0.65 | nM | 9.19 |
| CHEMBL27852 | — | Ki | = | 0.85 | nM | 9.07 |
| CHEMBL28922 | — | Ki | = | 2.4 | nM | 8.62 |
| CHEMBL27852 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL285140 | — | Ki | = | 2000.0 | nM | 5.70 |