Assay Detail
Binding
CHEMBL813671
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition against human thrombin was determined
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis, evaluation, and crystallographic analysis of L-371,912: A potent and selective active-site thrombin inhibitor
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.18 | 10.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2062141 | — | — | 1 | 10.05 |
| CHEMBL125181 | — | — | 1 | 8.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2062141 | — | Ki | = | 0.09 | nM | 10.05 |
| CHEMBL125181 | — | Ki | = | 5.0 | nM | 8.30 |