Assay Detail
ADMET
CHEMBL813697
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Evaluated for cytotoxicity under aerobic conditions against UV4 cells using microassay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Cricetulus griseus |
| Cell Type | UV4 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Hypoxia-selective antitumor agents. 3. Relationships between structure and cytotoxicity against cultured tumor cells for substituted N,N-bis(2-chloroethyl)anilines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.97 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL283163 | — | — | 1 | 7.70 |
| CHEMBL19336 | — | — | 1 | 6.48 |
| CHEMBL282006 | — | — | 1 | 6.23 |
| CHEMBL19773 | — | — | 1 | 5.86 |
| CHEMBL283774 | — | — | 1 | 5.55 |
| CHEMBL20152 | — | — | 1 | 5.28 |
| CHEMBL19995 | — | — | 1 | 4.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL283163 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL19336 | — | IC50 | = | 330.0 | nM | 6.48 |
| CHEMBL282006 | — | IC50 | = | 590.0 | nM | 6.23 |
| CHEMBL19773 | — | IC50 | = | 1390.0 | nM | 5.86 |
| CHEMBL283774 | — | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL20152 | — | IC50 | = | 5300.0 | nM | 5.28 |
| CHEMBL19995 | — | IC50 | = | 22000.0 | nM | 4.66 |