Assay Detail
Functional
CHEMBL813698
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Evaluated for growth inhibition of UV-4 cells under aerobic conditions
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cricetulus griseus |
| Cell Type | UV4 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Hypoxia-selective antitumor agents. 3. Relationships between structure and cytotoxicity against cultured tumor cells for substituted N,N-bis(2-chloroethyl)anilines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.01 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL19868 | — | — | 1 | 7.10 |
| CHEMBL538221 | — | — | 1 | 6.80 |
| CHEMBL19668 | — | — | 1 | 6.32 |
| CHEMBL19774 | — | — | 1 | 6.28 |
| CHEMBL281788 | — | — | 1 | 4.87 |
| CHEMBL19995 | — | — | 1 | 4.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL19868 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL538221 | — | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL19668 | — | IC50 | = | 480.0 | nM | 6.32 |
| CHEMBL19774 | — | IC50 | = | 520.0 | nM | 6.28 |
| CHEMBL281788 | — | IC50 | = | 13600.0 | nM | 4.87 |
| CHEMBL19995 | — | IC50 | = | 22000.0 | nM | 4.66 |