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Assay Detail

CHEMBL814124

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested in vitro for inhibitory activity against thermolysin
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Thermolysin (CHEMBL3392)
Type SINGLE PROTEIN
Organism Bacillus thermoproteolyticus

Publication

Thiol and hydroxamic acid containing inhibitors of endothelin converting enzyme
Bertenshaw SR, Talley JJ, Rogers RS, Carter JS, Moore WM, Branson LM, Koboldt CM
Bioorg Med Chem Lett (1993) 3 : 1953 -1958
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.19 7.19

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2372437 1 7.19

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2372437 IC50 = 64.0 nM 7.19