Assay Detail
Binding
CHEMBL814145
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity (50 uM) against HSV-1 Thymidine kinase in OST-TK-/HSV-1 TK+ cell line in combination with BVAraU
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human alphaherpesvirus 1 |
| Cell Type | OST-TK-/HSV-1 TK+ |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.80 | 7.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL52609 | DOXRIBTIMINE | 2.0 | 1 | 7.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL52609 | DOXRIBTIMINE | IC50 | = | 16.0 | nM | 7.80 |