Assay Detail
Functional
CHEMBL814442
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Functional activity in RAT-1cells, transiently-transfected with human TP-receptor (% of control ligand, [3H]-U-46,619=100%)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and in vitro evaluation of human FP-receptor selective prostaglandin analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.07 | 5.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2220404 | CLOPROSTENOL | 2.0 | 1 | 5.62 |
| CHEMBL36817 | — | — | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2220404 | CLOPROSTENOL | EC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL36817 | — | EC50 | = | 30000.0 | nM | 4.52 |