Assay Detail
Binding
CHEMBL814620
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Inhibition of Tyrosine protein kinase receptor TIE-2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Discovery of a new class of anilinoquinazoline inhibitors with high affinity and specificity for the tyrosine kinase domain of c-Src.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.95 | 4.95 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL169186 | — | — | 1 | 4.95 |
| CHEMBL170984 | — | — | 1 | 4.95 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL169186 | — | IC50 | = | 11300.0 | nM | 4.95 |
| CHEMBL170984 | — | IC50 | = | 11300.0 | nM | 4.95 |