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Assay Detail

CHEMBL814732

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for the receptor binding studies with Thromboxane A2 receptor using [3H]-SQ 29548 as radioligand in human platelet membranes.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Thromboxane A2 receptor (CHEMBL2069)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Interphenylene 7-oxabicyclo[2.2.1]heptanes. SQ33,961: a new potent, long-acting thromboxane antagonist
Misra RN, Brown BR, Sher PM, Patel MM, Goldenberg HJ, Michel IM, Harris DN
Bioorg Med Chem Lett (1991) 1 : 461 -464
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 10.00 10.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL31765 1 10.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL31765 Kd = 0.1 nM 10.00