Assay Detail
Binding
CHEMBL814734
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for inhibition of specific binding of [3H]-SQ 29,548 to thromboxane A2 receptor in human platelet membranes
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Interphenylene 7-oxabicyclo[2.2.1]heptane thromboxane A2 antagonists. Semicarbazone omega-chains.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 7 | 7.28 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL95872 | — | — | 1 | 9.00 |
| CHEMBL95884 | — | — | 1 | 8.22 |
| CHEMBL95867 | — | — | 1 | 7.68 |
| CHEMBL318426 | — | — | 1 | 7.41 |
| CHEMBL99041 | — | — | 1 | 6.77 |
| CHEMBL99348 | — | — | 1 | 5.97 |
| CHEMBL318673 | — | — | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL95872 | — | Kd | = | 1.0 | nM | 9.00 |
| CHEMBL95884 | — | Kd | = | 6.0 | nM | 8.22 |
| CHEMBL95867 | — | Kd | = | 21.1 | nM | 7.68 |
| CHEMBL318426 | — | Kd | = | 39.4 | nM | 7.41 |
| CHEMBL99041 | — | Kd | = | 171.0 | nM | 6.77 |
| CHEMBL99348 | — | Kd | = | 1070.0 | nM | 5.97 |
| CHEMBL318673 | — | Kd | = | 1196.0 | nM | 5.92 |