Assay Detail
Binding
CHEMBL814943
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Binding affinity against Thrombin.
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Protease inhibitors: current status and future prospects.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 9.30 | 10.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL289395 | — | — | 1 | 10.25 |
| CHEMBL40854 | — | — | 1 | 9.68 |
| CHEMBL364255 | — | — | 1 | 8.82 |
| CHEMBL138877 | — | — | 1 | 8.44 |
| CHEMBL19902 | DX-9065A | — | 1 | - |
| CHEMBL20240 | YM-60828 | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL289395 | — | Ki | = | 0.056 | nM | 10.25 |
| CHEMBL40854 | — | Ki | = | 0.21 | nM | 9.68 |
| CHEMBL364255 | — | Ki | = | 1.5 | nM | 8.82 |
| CHEMBL138877 | — | Ki | = | 3.6 | nM | 8.44 |
| CHEMBL19902 | DX-9065A | Ki | > | 2000000.0 | nM | - |
| CHEMBL20240 | YM-60828 | Ki | > | 100000.0 | nM | - |