Assay Detail
Binding
CHEMBL814965
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition constant was evaluated for inhibitory activity against the blood coagulant thrombin
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Solid phase synthesis of benzylamine-derived sulfonamide library.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 5.88 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL83345 | — | — | 1 | 8.00 |
| CHEMBL266196 | — | — | 1 | 7.30 |
| CHEMBL164661 | — | — | 1 | 6.70 |
| CHEMBL162929 | — | — | 1 | 6.22 |
| CHEMBL162315 | — | — | 1 | 5.51 |
| CHEMBL350751 | — | — | 1 | 4.81 |
| CHEMBL165195 | — | — | 1 | 4.50 |
| CHEMBL349653 | — | — | 1 | 4.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL83345 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL266196 | — | Ki | = | 50.0 | nM | 7.30 |
| CHEMBL164661 | — | Ki | = | 200.0 | nM | 6.70 |
| CHEMBL162929 | — | Ki | = | 600.0 | nM | 6.22 |
| CHEMBL162315 | — | Ki | = | 3060.0 | nM | 5.51 |
| CHEMBL350751 | — | Ki | = | 15600.0 | nM | 4.81 |
| CHEMBL165195 | — | Ki | = | 31700.0 | nM | 4.50 |
| CHEMBL349653 | — | Ki | = | 97200.0 | nM | 4.01 |