Assay Detail
Binding
CHEMBL814970
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against thrombin
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
New 4-point pharmacophore method for molecular similarity and diversity applications: overview of the method and applications, including a novel approach to the design of combinatorial libraries containing privileged substructures.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.86 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL51173 | — | — | 1 | 8.22 |
| CHEMBL1160894 | — | — | 1 | 7.72 |
| CHEMBL23813 | — | — | 1 | 7.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL51173 | — | Ki | = | 6.0 | nM | 8.22 |
| CHEMBL1160894 | — | Ki | = | 19.0 | nM | 7.72 |
| CHEMBL23813 | — | Ki | = | 23.0 | nM | 7.64 |