Assay Detail
Binding
CHEMBL815018
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of thromboxane TXA2 synthetase from human platelets
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Selective thromboxane synthetase inhibitors. 4. 2-(1H-imidazol-1-ylmethyl) carboxylic acids of benzo[b]furan, benzo[b]thiophene, indole, and naphthalene.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.06 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267473 | DAZOXIBEN | 2.0 | 1 | 8.52 |
| CHEMBL44365 | — | — | 1 | 7.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267473 | DAZOXIBEN | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL44365 | — | IC50 | = | 25.0 | nM | 7.60 |