Assay Detail
Functional
CHEMBL815107
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of tubulin polymerization in S180 (murine sarcoma) cells.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | CCRF S-180 |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Antitumor activity of unsaturated fatty acid esters of 4'-demethyldeoxypodophyllotoxin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.70 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL89905 | 4'-DEMETHYLDEOXYPODOPHYLLOTOXIN | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL89905 | 4'-DEMETHYLDEOXYPODOPHYLLOTOXIN | IC50 | = | 2000.0 | nM | 5.70 |