Assay Detail
Binding
CHEMBL815148
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against bovine pancreatic trypsin was determined
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Active site-directed synthetic thrombin inhibitors: synthesis, in vitro and in vivo activity profile of BMY 44621 and analogs. An examination of the role of the amino group in the D-Phe-Pro-Arg-H series.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.12 | 7.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL319227 | — | — | 1 | 7.58 |
| CHEMBL319396 | — | — | 1 | 6.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL319227 | — | EC50 | = | 26.0 | nM | 7.58 |
| CHEMBL319396 | — | EC50 | = | 220.0 | nM | 6.66 |