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Assay Detail

CHEMBL815303

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Functional
Effective concentration required to inhibit UT7/TPO cell proliferation was determined.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type UT7/TPO
Confidence 3 — Cell-line / Tissue
Curated By Autocuration

Publication

Hydrazinonaphthalene and azonaphthalene thrombopoietin mimics are nonpeptidyl promoters of megakaryocytopoiesis.
Duffy KJ, Darcy MG, Delorme E, Dillon SB, Eppley DF, Erickson-Miller C, Giampa L, Hopson CB, Huang Y, Keenan RM, Lamb P, Leong L, Liu N, Miller SG, Price AT, Rosen J, Shah R, Shaw TN, Smith H, Stark KC, Tian SS, Tyree C, Wiggall KJ, Zhang L, Luengo JI.
J Med Chem (2001) 44 : 3730 -3745
PubMed 11606138 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.30 6.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3144787 1 6.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3144787 EC50 = 500.0 nM 6.30