Assay Detail
Functional
CHEMBL815529
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Inhibition of N1E-115 cells Kv channels
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | N1E-115 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Angular methoxy-substituted furo- and pyranoquinolinones as blockers of the voltage-gated potassium channel Kv1.3.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.45 | 4.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL282441 | — | — | 1 | 4.51 |
| CHEMBL23022 | — | — | 1 | 4.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL282441 | — | IC50 | = | 31000.0 | nM | 4.51 |
| CHEMBL23022 | — | IC50 | = | 42000.0 | nM | 4.38 |