Assay Detail
Binding
CHEMBL815925
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for inhibitory activity against human platelet microsomal TXA2 synthase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Structure-activity relationships in an imidazole-based series of thromboxane synthase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.52 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL38825 | — | — | 1 | 5.96 |
| CHEMBL39172 | — | — | 1 | 5.70 |
| CHEMBL41908 | — | — | 1 | 5.28 |
| CHEMBL39150 | — | — | 1 | 5.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL38825 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL39172 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL41908 | — | IC50 | = | 5300.0 | nM | 5.28 |
| CHEMBL39150 | — | IC50 | = | 7100.0 | nM | 5.15 |