Assay Detail
Functional
CHEMBL816071
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Thrombin generation was determined
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and pharmacological properties of a close analogue of an antithrombotic pentasaccharide (SR 90107A/ORG 31540).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.93 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1909451 | — | — | 1 | 6.96 |
| CHEMBL609990 | — | — | 1 | 6.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1909451 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL609990 | — | IC50 | = | 130.0 | nM | 6.89 |