Assay Detail
Functional
CHEMBL816379
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The effective concentration to show 50% of activity was measured on varicella zoster virus(VZV) cell culture
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human alphaherpesvirus 3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Structure-activity relationships of (E)-5-(2-bromovinyl)uracil and related pyrimidine nucleosides as antiviral agents for herpes viruses.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.81 | 6.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1540 | PENCICLOVIR | 4.0 | 1 | 6.85 |
| CHEMBL85809 | — | — | 1 | 4.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1540 | PENCICLOVIR | EC50 | = | 140.0 | nM | 6.85 |
| CHEMBL85809 | — | EC50 | = | 17000.0 | nM | 4.77 |