Assay Detail
Binding
CHEMBL816482
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Apparent binding affinity on rat 5-alpha reductase isozyme
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Pharmacological options in the treatment of benign prostatic hyperplasia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.52 | 7.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL278283 | — | — | 1 | 7.46 |
| CHEMBL578029 | — | — | 1 | 7.16 |
| CHEMBL283217 | — | — | 1 | 6.80 |
| CHEMBL24969 | — | — | 1 | 6.70 |
| CHEMBL27862 | — | — | 1 | 6.45 |
| CHEMBL24825 | — | — | 1 | 5.77 |
| CHEMBL24249 | — | — | 1 | 5.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL278283 | — | Ki | = | 35.0 | nM | 7.46 |
| CHEMBL578029 | — | Ki | = | 70.0 | nM | 7.16 |
| CHEMBL283217 | — | Ki | = | 160.0 | nM | 6.80 |
| CHEMBL24969 | — | Ki | = | 200.0 | nM | 6.70 |
| CHEMBL27862 | — | Ki | = | 356.0 | nM | 6.45 |
| CHEMBL24825 | — | Ki | = | 1700.0 | nM | 5.77 |
| CHEMBL24249 | — | Ki | = | 5300.0 | nM | 5.28 |