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Assay Detail

CHEMBL816888

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Tested for inhibition of polymerization of tubulin
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Tubulin alpha chain (CHEMBL3658)
Type SINGLE PROTEIN
Organism Sus scrofa

Publication

Potent antimitotic and cell growth inhibitory properties of substituted chalcones.
Ducki S, Forrest R, Hadfield JA, Kendall A, Lawrence NJ, McGown AT, Rennison D.
Bioorg Med Chem Lett (1998) 8 : 1051 -1056
PubMed 9871706 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.92 7.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL9652 1 7.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL9652 IC50 = 12.0 nM 7.92