Assay Detail
Functional
CHEMBL817371
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested in vitro for inhibitory activity against type 1 5-alpha reductase Isozyme homogenated from rat epididymis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (CHEMBL5099) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Indole derivatives as a new class of steroid 5 alpha-reductase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.75 | 6.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL24470 | — | — | 1 | 6.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL24470 | — | IC50 | = | 180.0 | nM | 6.75 |