Assay Detail
Binding
CHEMBL817570
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Compound was evaluated for its inhibitory activity against bovine trypsin
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Potent and efficacious thienylamidine-incorporated thrombin inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.07 | 6.87 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL296956 | — | — | 1 | 6.87 |
| CHEMBL298013 | — | — | 1 | 6.82 |
| CHEMBL48133 | — | — | 1 | 6.82 |
| CHEMBL46842 | — | — | 1 | 5.61 |
| CHEMBL7962 | — | — | 1 | 5.50 |
| CHEMBL7656 | — | — | 1 | 4.79 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL296956 | — | Ki | = | 134.0 | nM | 6.87 |
| CHEMBL298013 | — | Ki | = | 153.0 | nM | 6.82 |
| CHEMBL48133 | — | Ki | = | 150.0 | nM | 6.82 |
| CHEMBL46842 | — | Ki | = | 2440.0 | nM | 5.61 |
| CHEMBL7962 | — | Ki | = | 3200.0 | nM | 5.50 |
| CHEMBL7656 | — | Ki | = | 16200.0 | nM | 4.79 |