Assay Detail
Binding
CHEMBL817579
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition against bovine trypsin was determined
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis, evaluation, and crystallographic analysis of L-371,912: A potent and selective active-site thrombin inhibitor
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.45 | 5.94 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2062141 | — | — | 1 | 5.94 |
| CHEMBL125181 | — | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2062141 | — | Ki | = | 1150.0 | nM | 5.94 |
| CHEMBL125181 | — | Ki | = | 11000.0 | nM | 4.96 |