Assay Detail
Binding
CHEMBL817625
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound (isomer) was tested in the absence of light for inhibitory activity against trypsin.
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
(Z,Z)-2,7-Bis(4-amidinobenzylidene)cycloheptan-1-one: identification of a highly active inhibitor of blood coagulation factor Xa.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 7.00 | 7.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL94336 | — | — | 1 | 7.54 |
| CHEMBL55035 | — | — | 1 | 7.48 |
| CHEMBL331437 | — | — | 1 | 7.36 |
| CHEMBL325022 | — | — | 1 | 6.70 |
| CHEMBL48233 | — | — | 1 | 6.55 |
| CHEMBL326552 | — | — | 1 | 6.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL94336 | — | Ki | = | 29.0 | nM | 7.54 |
| CHEMBL55035 | — | Ki | = | 33.0 | nM | 7.48 |
| CHEMBL331437 | — | Ki | = | 44.0 | nM | 7.36 |
| CHEMBL325022 | — | Ki | = | 200.0 | nM | 6.70 |
| CHEMBL48233 | — | Ki | = | 280.0 | nM | 6.55 |
| CHEMBL326552 | — | Ki | = | 410.0 | nM | 6.39 |