Assay Detail
Binding
CHEMBL817652
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The inhibition constant (Ki(nM)) by displacement of [125I]- HO-LVA radiolabeled ligand using membranes of CHO cells of human Vasopressin V1b receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Fluorescent pseudo-peptide linear vasopressin antagonists: design, synthesis, and applications.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.48 | 8.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL262035 | — | — | 1 | 8.03 |
| CHEMBL540192 | — | — | 1 | 7.57 |
| CHEMBL412210 | — | — | 1 | 6.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL262035 | — | Ki | = | 9.4 | nM | 8.03 |
| CHEMBL540192 | — | Ki | = | 27.0 | nM | 7.57 |
| CHEMBL412210 | — | Ki | = | 142.0 | nM | 6.85 |