Assay Detail
Binding
CHEMBL818130
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Concentration required to reduce the amount of pelleted tubulin
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Cryptophycin affinity labels: synthesis and biological activity of a benzophenone analogue of cryptophycin-24.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.13 | 5.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL441018 | CRYPTOPHYCIN A | — | 1 | 5.43 |
| CHEMBL165020 | — | — | 1 | 5.13 |
| CHEMBL264224 | ARENASTATIN A | — | 1 | 4.82 |
| CHEMBL166221 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL441018 | CRYPTOPHYCIN A | IC50 | = | 3700.0 | nM | 5.43 |
| CHEMBL165020 | — | IC50 | = | 7400.0 | nM | 5.13 |
| CHEMBL264224 | ARENASTATIN A | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL166221 | — | IC50 | > | 100000.0 | nM | - |