Assay Detail
Binding
CHEMBL818393
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Binding affinity to VDR receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
New dermatological agents for the treatment of psoriasis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 9.97 | 10.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL846 | CALCITRIOL | 4.0 | 1 | 10.19 |
| CHEMBL318267 | — | — | 1 | 10.14 |
| CHEMBL318617 | — | — | 1 | 10.05 |
| CHEMBL1200666 | CALCIPOTRIENE | 4.0 | 1 | 9.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL846 | CALCITRIOL | Kd | = | 0.065 | nM | 10.19 |
| CHEMBL318267 | — | Kd | = | 0.073 | nM | 10.14 |
| CHEMBL318617 | — | Kd | = | 0.089 | nM | 10.05 |
| CHEMBL1200666 | CALCIPOTRIENE | Kd | = | 0.31 | nM | 9.51 |