Assay Detail
Functional
CHEMBL818589
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Comparative Potency (IC50s) at HSV-1 passage 4 in vero cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Chlorocebus sabaeus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Antiviral activities of methylated nordihydroguaiaretic acids. 2. Targeting herpes simplex virus replication by the mutation insensitive transcription inhibitor tetra-O-methyl-NDGA.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.22 | 5.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL90983 | TERAMEPROCOL | 2.0 | 1 | 5.22 |
| CHEMBL184 | ACYCLOVIR | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL90983 | TERAMEPROCOL | IC50 | = | 5970.0 | nM | 5.22 |
| CHEMBL184 | ACYCLOVIR | IC50 | = | 138400.0 | nM | - |