Assay Detail
Functional
CHEMBL818671
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of anandamide transport(ANT) was determined against human lymphoma U937 cell using [3H]anandamide as radioligand
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | U-937 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, and biological evaluation of new inhibitors of the endocannabinoid uptake: comparison with effects on fatty acid amidohydrolase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.93 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL287130 | — | — | 1 | 5.10 |
| CHEMBL287364 | — | — | 1 | 4.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL287130 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL287364 | — | IC50 | = | 18000.0 | nM | 4.75 |